MicroRNAs are non‐coding regulators of gene expression and key factors in development, disease, and targets for bioengineering. Consequently, microRNAs have become essential elements of already burgeoning draft plant genome descriptions where their annotation is often particularly poor, contributing unduly to the corruption of public databases. Using the Citrus sinensis as an example, we highlight and review common failings of miRNAome annotations. Understanding and exploiting the role of miRNAs in plant biology will be stymied unless the research community acts decisively to (...) improve the accuracy of miRNAome annotations. We encourage genome annotation teams to do it right or not at all. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Who or What is the Preembryo?S.J. Richard A. McCormick (bio)IntroductionAlthough widely used by scientists, the term "preembryo" has raised some suspicions. Histopathologist Michael Jarmulowicz (1990), for example, asserts that the term was adopted by the American Fertility Society (AFS) and the Voluntary Licensing Authority (VLA) in Britain "as an exercise of linguistic engineering to make human embryo research more palatable to the general public."I cannot speak for the (...) VLA, but I can clarify that this was not the motive of the AFS. As a member of the AFS ethics committee that discussed and adopted this terminology, I know that our discussion was not tied to embryo research or moral issues. The term "preembryo" was adopted because the earliest stages of mammalian development primarily involve establishment of the nonembryonic trophoblast, rather than the formation of the embryo. As Clifford Grobstein (1988, p. 61), a distinguished basic scientist who also sat on the AFS committee notes:The scientific rationale for the term preembryo... is its greater accuracy in characterizing the initial phase of mammalian and human development.... The status implications of such a change in terminology were not at issue in the discussion.This is not to say that the moral status of the preembryo is not a concern worthy of independent consideration. It is an important question with significant practical implications, especially in the context of in vitro fertilization. At stake are issues such as: (1) what may be done to preembryos before transfer; (2) whether all preembryos must be transferred; and (3) what may be done to preembryos that are not transferred (Ethics Committee of the American Fertility Society (AFS) 1986, p. 29S). Furthermore, emergency treatment of rape cases may also depend on such a determination. [End Page 1]Cryopreservation, which entails freezing unused preembryos for possible later use, is one example of a procedure that raises issues associated with the moral status of the preembryo. Cryopreservation decreases the number of stimulated egg recovery cycles a woman must undergo and increases flexibility in transfer protocols. But thawing of the preembryos is not a completely benign process; significant numbers of the preembryos die in the process and injury cannot be excluded.In addition, down the road a year or so lies preimplantation genetic diagnosis, now being tested in several centers of reproductive research. This would involve the removal of one or more cells from a preembryo developing in vitro. The DNA from these cells would be studied and then only genetically normal preembryos would be transferred. With the growth in knowledge about single gene defects and the rapid advance of amplification technology, which allows gene visualization, it is not difficult to imagine scientists embarking on a variety of micromanipulations of the preembryo for the sake of gaining knowledge.Not all research with gametes involves preembryos, but clearly some experiments and procedures await resolution of the moral status of the preembryo. I contend in this paper that the moral status—and specifically the controversial issue of personhood—is related to attainment of developmental individuality (being the source of one individual). This contrasts with the view that holds that personhood occurs earlier, at the point of genetic uniqueness. I believe that an embryo that has developed to the point where it can be one individual and one individual only, differs in moral status from a preembryo that has not, even if in many cases we may choose to treat them similarly.The Scientific UnderpinningsTwo things must be kept in mind—and in a sense, in tension—in turning to science for help in assessing the status of the preembryo. First, science is not competent to decide the question of personhood or ensoulment. As the Catholic document, Declaration on Procured Abortion, which I will return to later, notes: "It is a philosophical problem" (Congregation for the Doctrine of the Faith (CDF) 1974, p. 10, endnote 19). On the other hand, another Catholic document, Donum vitae(CDF 1987), notes that the conclusions of science provide a "valuable indication" for reason's deliberations about personhood. We might say that if science cannot decide the question of personhood, neither can it be decided without science.For my review of embryological science... (shrink)

This book assesses how Vatican II opened up the Catholic Church to encounter, dialogue, and engagement with other world religions. Opening with a contribution from the President of the Pontifical Council for Interreligious Dialogue, Cardinal Jean-Louis Tauran, it next explores the impact, relevance, and promise of the Declaration Nostra Aetate before turning to consider how Vatican II in general has influenced interfaith dialogue and the intellectual and comparative study of world religions in the postconciliar decades, as well as the contribution (...) of particular past and present thinkers to the formation of current interreligious and comparative theological methods. Additionally, chapters consider interreligious dialogue vis-à-vis theological anthropology in conciliar documents; openness to the spiritual practices of other faith traditions as a way of encouraging positive interreligious encounter; the role of lay and new ecclesial movements in interreligious dialogue; and the development of Monastic Interreligious Dialogue. Finally, it includes a range of perspectives on the fruits and future of Vatican’s II’s opening to particular faiths such as Judaism, Islam, Hinduism, and Buddhism. (shrink)

ISBN-13: 978-1934074480
Plot Summary from the book:
"An aristocratic young man, fed up with his studies, contemplates military service. His teacher is unable by any reasoning to call him back him from the path he has embarked upon. The young man enlists another youth who commits himself to the journey, dressed in military garb, and he happens upon two deserting soldiers, unsightly and ill-used both in their dress and in their hygiene. Both young men are so moved by the deserters’ (...) remarks deploring and reviling their lot in life that they return to their studies. One of the deserters, however, hopes to be welcomed back by the wife and small children he had deserted and left penniless and bereft of friends. She gives him a nasty reception, with verbal and corporal abuse, and he barely manages to have his sin forgiven and to return to her good graces."
From the Table of Contents:
Introduction
How to Use this Book
Jacobus Pontanus: Biography
Jesuit Comedy – Seriously?
The Stratocles as a Spiritual Exercise
Just War and the Morality of Military Service
A Play about War and the Real Wars of Pontanus' Time
The Characters and Their Names
Pontanus’ Use of Classical Sources
The History of the Text of Stratocles
Performance
Stratocles or War
Endnotes
Appendices
Pontanus on Humanist Studies
Pontanus on Writing Comedy
Renaissance School Hazing, called “Deposition”
Anonymous: Instructions for Deposition
Dialogue on Hazing (Progymnasma 100)
. (shrink)

William Lawrence Tower’s work on the evolution of the Colorado Potato Beetle (_Leptinotarsa decemlineata_), documenting the environmental induction of mutation and speciation, made him a leading figure in experimental genetics during the first decade of the 20th century. His research program served as a model for other experimental evolution studies seeking to demonstrate the environmental modification of inheritance. Tower enjoyed the support of influential figures in the field, despite well-known problems that plagued Tower’s earlier academic career. The validity of his (...) genetic work, and other findings reported by Tower, were later challenged. The Tower affair illustrates how questionable and possibly fraudulent scientific practices can be tolerated to explore certain experimental directions and theoretical frameworks, particularly at the frontier of expanding disciplines. When needed, those explorations can be forestalled or extinguished by exploiting conspicuous vulnerabilities of rogue practitioners. In Tower’s case, both unrefuted allegations of scientific misconduct and personal problems dissolved his institutional support, leading to a swift ouster from academic science. Tower’s downfall discredited soft inheritance and neo-Lamarckian conceptions in the field of experimental genetics, facilitating the discipline’s embrace of a hard inheritance model that featured a hereditary material resistant to environmental modification. (shrink)

The present article has three sections. The first one discusses the relationship of the theological theory of transubstantiation to that of transignification and transfinalization , ideas that were introduced just before the time of Vatican II by northern European theologians. The second section develops a holistic view of the nature of matter. Our present scientific knowledge seems to require that we abandon the Aristotelian theory of hylomorphism in favor of a theory in which real beings of a certain level ‘sublate’ (...) real but subordinate beings of lower levels. For example, a human being is a substance that includes within itself many smaller substances. When he was in the flesh, the physical body of Christ included within itself a vast number of interconnected atoms and molecules. The third section discusses ideas of Teilhard de Chardin about the relationship of Christ to matter. (shrink)

"All art should become science and all science art; poetry and philosophy should be made one." Friedrich Schlegel's words perfectly capture the project of the German Romantics, who believed that the aesthetic approaches of art and literature could reveal patterns and meaning in nature that couldn't be uncovered through rationalistic philosophy and science alone. In this wide-ranging work, Robert J. Richards shows how the Romantic conception of the world influenced (and was influenced by) both the lives of the people who (...) held it and the development of nineteenth-century science. Integrating Romantic literature, science, and philosophy with an intimate knowledge of the individuals involved—from Goethe and the brothers Schlegel to Humboldt and Friedrich and Caroline Schelling—Richards demonstrates how their tempestuous lives shaped their ideas as profoundly as their intellectual and cultural heritage. He focuses especially on how Romantic concepts of the self, as well as aesthetic and moral considerations—all tempered by personal relationships—altered scientific representations of nature. Although historians have long considered Romanticism at best a minor tributary to scientific thought, Richards moves it to the center of the main currents of nineteenth-century biology, culminating in the conception of nature that underlies Darwin's evolutionary theory. Uniting the personal and poetic aspects of philosophy and science in a way that the German Romantics themselves would have honored, The Romantic Conception of Life alters how we look at Romanticism and nineteenth-century biology. (shrink)

When Charles Darwin (1859, 482) wrote in the Origin of Species that he looked to the “young and rising naturalists” to heed the message of his book, he likely had in mind individuals like Ernst Haeckel (1834-1919), who responded warmly to the invitation (Haeckel, 1862, 1: 231-32n). Haeckel became part of the vanguard of young scientists who plowed through the yielding turf to plant the seed of Darwinism deep into the intellectual soil of Germany. As Haeckel would later observe, the (...) seed flourished in extremely favorable ground. The German mind, he would write (1868), was predisposed to adopt the new theory. The great philosopher Immanuel Kant (1724- 1804), for instance, was on the verge of accepting a transmutational view in his Third Critique (1790; 1957, 538-39), though he stepped gingerly back from the temptation. Johann Wolfgang von Goethe (1749-1832), about the same time, dallied with transmutational ideas, at least Haeckel would convince Darwin that the Englishman had an illustrious predecessor. Jean-Baptiste de Lamarck’s (1744-1829) conceptions had taken hold among several major German thinkers in the first few decades of the nineteenth century in a way they had not in England and France. Among those ready to declare themselves for the new dispensation was Rudolf Virchow (1821-1902), Haeckel’s teacher at Würzburg—though, this very political scientist would prove Haeckel’s nemesis later in the century. So Haeckel’s estimate of the ripeness of German thought was not off the mark. Darwinism took hold in the newly unified land, though not without some struggle; but at last it became the dominant view in the biological sciences. But with its success did it foster the malign racist ideology that transfixed Adolf Hitler (1889-1945)? (shrink)

Thomas Henry Huxley recalled that after he had read Darwin’s Origin of Species, he had exclaimed to himself: “How extremely stupid not to have thought of that!” (Huxley,1900, 1: 183). It is a famous but puzzling remark. In his contribution to Francis Darwin’s Life and Letters of Charles Darwin, Huxley rehearsed the history of his engagement with the idea of transmutation of species. He mentioned the views of Robert Grant, an advocate of Lamarck, and Robert Chambers, who anonymously published Vestiges (...) of the Natural History of Creation (1844), which advanced a crude idea of transmutation. He also recounted his rejection of Agassiz’s belief that species were progressively replaced by the divine hand. He neglected altogether his friend Herbert Spencer’s early Lamarckian ideas about species development, which were also part of the long history of his encounters with the theory of descent. None of these sources moved him to adopt any version of the transmutation hypothesis. (shrink)

The eminent historian and philosopher of biology, Michael Ruse, has written several books that explore the relationship of evolutionary theory to its larger scientific and cultural setting. Among the questions he has investigated are: Is evolution progressive? What is its epistemological status? Most recently, in "Darwin and Design: Does Evolution have a Purpose?," Ruse has provided a history of the concept of teleology in biological thinking, especially in evolutionary theorizing. In his book, he moves quickly from Plato and Aristotle to (...) Kant and such British thinkers as Paley and Whewell. His main focus, though, is on Darwin's theory and its subsequent fate. Ruse rests his history on some shaky historical and philosophic assumptions, particularly the unexamined notion that evolutionary theory is an abstract entity that is unproblematically realized in different historical periods. He also assumes that Darwin conceived nature as if it were a Manchester spinning loom -- a clanking, dispassionate machine. A more subtle analysis, which Ruse eschews, might discover that Darwin's conception of nature owed a strong debt to German Romanticism and that he contrived to infuse nature with moral and aesthetic values, not to suck them from nature. Ruse proves he is a thinker to contend with, and this essay is quite contentious. (shrink)

Who can divine the intentions of the human heart, the motives that guide behavior? Some of the reasons for our actions lie on the surface of consciousness, whereas others are more deeply embedded in the recesses of the mind. Recovering motives and intentions is a principal job of the historian. For without some attribution of mental attitudes, actions cannot be characterized and decisions assessed. The same overt behavior, after all, might be described as “mailing a letter” or “fomenting a revolution.” (...) The recovery of intentions is crucial for the historian’s narrative. (shrink)

Scholars have usually given Darwin’s theory a neo-Darwinian interpretation. A more careful examination of the language of Darwin’s notebooks and the language of the Origin of Species indicates that he reconstructed nature with a definite purpose: the final goal of man as a moral creature. In the aftermath of the Origin, Darwin, however, became more circumspect.

Many revolutionary proposals entered the biological disciplines during the late eighteenth and nineteenth centuries, theories that provided the foundations for today’s science and gave structure to its various branches. Cell theory, evolutionary theory, and genetics achieved their modern form during this earlier time. The period also saw a variety of new, auxiliary hypotheses that supplied necessary supports for the more comprehensive theories. These included ideas in morphology, embryology, systematics, language, and behavior. These scientific developments forced a reconceptualization of nature and (...) the place of human beings therein. The legacy for the twentieth and twenty-first centuries has been a materialization and mechanization of the most fundamental processes of life. From our current perspective, it’s easy to look back and assume that the foundational ideas of our contemporary science must have had the same character as they now seem to manifest. I think a closer inspection of biological science of this earlier period will reveal a discipline whose philosophic assumptions are quite different from those of its present incarnation. This becomes especially vivid when 1 we focus on the contributions of German Idealism and Romanticism to the biology of the earlier dispensation. (shrink)

In 1853, two decades after Goethe’s death, Hermann von Helmholtz, who had just become professor of anatomy at Königsberg, delivered an evaluation of the poet=s contributions to science.1 The young Helmholtz lamented Goethe=s stubborn rejection of Newton =s prism experiments. Goethe=s theory of light and color simply broke on the rocks of his poetic genius. The tragedy, though, was not repeated in biological science. In Helmholtz=s estimation, Goethe had advanced in this area two singular and “uncommonly fruitful” ideas.2 The poet (...) recognized, first, that the anatomical structures of various kinds of animals revealed a unity type underlying the superficial differences arising from variability of food, habit, and locality. His second lasting achievement was the related theory of the metamorphosis of organisms: the thesis that the various articulations within an organism developed out of a more basic kind of structure—that, for instance, the different parts of plants were metamorphosed leaves or that the various bones of the animal skull were but transformed vertebrae. These two general morphological conceptions, according to Helmholtz, grounded the biology flourishing at 1 mid-century. Goethe came to these ideas, Helmholtz shrewdly maintained, as the result of a poetically intuitive conception.3 He described, for instance, Goethe=s immediate recognition, while playfully tossing around a sheep=s skull on the Lido in Venice, that the fused bones of the battered cranium consisted of transmuted vertebrae. This experience resulted in the poet=s vertebral theory of the skull, which became a standard conception in later morphology.4 Poetic intuition thus liberated an idea initially embedded in matter and made it available to the analytic understanding of the scientist. Forty years later, in 1892, at the meeting of the Goethe Society in Weimar, Helmholtz returned to reexamine the poet=s scientific accomplishments, and, it would seem, implicitly his own; for by the end of his career, Helmholtz himself had achieved a position in German culture only a few steps below that of Goethe.5 His evaluation of Goethe=s achievements in physical science was now more complex than his earlier assessment had been. (shrink)

In late winter of 1864, Charles Darwin received two folio volumes on radiolarians, a group of one-celled marine organisms that secreted siliceous skeletons of unusual geometry. The author, the young German biologist Ernst Haeckel (fig. 1), had himself drawn the figures for the extraordinary copper-etched illustrations that filled the second volume.1 The gothic beauty of the plates astonished Darwin (fig. 2 ), but he must also have been drawn to passages that applied his theory to construct the descent relations of (...) these little known creatures. He replied to Haeckel that the volumes "were the most magnificent works which I have ever seen, & I am proud to possess a copy from the author."2 Emboldened by his own initiative in contacting the famous naturalist, Haeckel, a few days later, sent Darwin a newspaper clipping that described a meeting of the Society of German Naturalists and Physicians at Stettin, which occurred during the previous autumn. The article gave an extended and laudatory account of Haeckel's lecture defending Darwin's theory.3 Darwin immediately replied in his second letter: "I.. (shrink)

Thomas S. Kuhn’s The Structure of Scientific Revolutions was a watershed event when it was published in 1962, upending the previous understanding of science as a slow, logical accumulation of facts and introducing, with the concept of the “paradigm shift,” social and psychological considerations into the heart of the scientific process. More than fifty years after its publication, Kuhn’s work continues to influence thinkers in a wide range of fields, including scientists, historians, and sociologists. It is clear that The Structure (...) of Scientific Revolutions itself marks no less of a paradigm shift than those it describes. In Kuhn’s “Structure of Scientific Revolutions” at Fifty, leading social scientists and philosophers explore the origins of Kuhn’s masterwork and its legacy fifty years on. These essays exhume important historical context for Kuhn’s work, critically analyzing its foundations in twentieth-century science, politics, and Kuhn’s own intellectual biography: his experiences as a physics graduate student, his close relationship with psychologists before and after the publication of Structure, and the Cold War framework of terms such as “world view” and “paradigm.”. (shrink)

Our image of Herbert Spencer is that of a bald, dyspeptic bachelor, spending his days in rooming houses, and fussing about government interference with individual liberties. Beatrice Webb, who knew him as a girl and young woman recalls for us just this picture. In her diary for January 4, 1885, she writes: Royal Academy private view with Herbert Spencer. His criticisms on art dreary, all bound down by the “possible” if not probable. That poor old man would miss me on (...) the whole more than any other mortal. Has real anxiety for my welfare—physical and mental. Told him story of my stopping cart horse in Hyde Park and policeman refusing to come off his beat to hold it. Want of public spirit in passers-by not stopping it before. “Yes, that is another instance of my first principle of government. Directly you get state intervention you cease to have public spirit in individuals; that will be a constantly increasing tendency and the State, like the policeman, will be so bound by red-tape rules that it will frequently leave undone the simplest duties.”1 Spencer appears a man whose strangled emotions would yet cling to a woman whose philosophy would be completely alien to his own, as Webb’s Fabian Socialism turned out to be. Our image of Darwin is more complex than our image of Spencer. We might think of him nestled in the bosom of his large family, kindly, and just a little sad. The photo of him taken by Julia Cameron reveals the visage of an Old Testament prophet, though one, not fearsome, but made wise by contemplating the struggle of life on this earth. These images have deeply colored our reaction to the ideas of each thinker. The pictures are not false, but they are cropped portraits that tend to distort our reactions to the theories of each. If we examine the major features of their respective. (shrink)

Just before Ernst Haeckel’s death in 1919, historians began piling on the faggots for a splendid auto-da-fé. Though more people prior to the Great War learned of Darwin’s theory through his efforts than through any other source, including Darwin himself, Haeckel has been accused of not preaching orthodox Darwinian doctrine. In 1916, E. S. Russell, judged Haeckel's principal theoretical work, Generelle Morphologie der Organismen, as "representative not so much of Darwinian as of pre-Darwinian thought."1 Both Stephen Jay Gould and Peter (...) Bowler endorse this evaluation, and see as an index of Haeckel’s heterodox deviation his use of the biogenetic law that ontogeny recapitulates phylogeny.2 Michael Ruse, without much analysis, simply proclaims that “Haeckel and friends were not true Darwinians.”3 These historians locate the problem in Haeckel’s inclinations toward Naturphilosophie and in his adoption of the kind of Romantic attitudes characterizing the earlier biology of Goethe. These charges of heresy assume, of course, that Darwin’s own theory harbors no taint of Romanticism and that it consequently remains innocent of the doctrine of recapitulation. I think both assumptions quite. (shrink)

If religion means a commitment to a set of theological propositions regarding the nature of God, the soul, and an afterlife, Ernst Haeckel (1834-1919) was never a religious enthusiast. The influence of the great religious thinker Friedrich Daniel Schleiermacher (1768-1834) on his family kept religious observance decorous and commitment vague.2 The theologian had maintained that true religion lay deep in the heart, where the inner person experienced a feeling of absolute dependence. Dogmatic tenets, he argued, served merely as inadequate symbols (...) of this fundamental experience. Religious feeling, according to Schleiermacher’s Über die Religion (On religion, 1799), might best be cultivated by seeking after truth, experiencing beauty, and contemplating nature.3 Haeckel practiced this kind of Schleiermachian religion all of his life. Haeckel’s association with the Evangelical Church, even as a youth, had been conventional. The death of his first wife severed the loose threads still holding him to formal observance. The power of that death, his obsession with a life that might have been, and the dark feeling of love forever lost drove him to find a more enduring and rational sub-. (shrink)

The Battle for the American Mind brings together religion, politics, economics, science, and literature to present a compelling history of the American people. In this brief and entertaining book, noted historian Carl J. Richard argues that there have been three worldviews that have dominated American thought—theism, humanism, and skepticism. By clearly explaining what Americans believed, exploring why they did so, and showing how that impacted the nation's development, Richard presents a unique portrait of the United States—past and present.

I exhort you never to debase the moral currency or to lower the standard of rectitude, but to try others by the final maxim that governs your own lives and to suffer no man and no cause to escape the undying penalty which history has the power to inflict on wrong.2 In 1902, the year after Acton died, the president of the American Historical association, Henry Lea, in dubious celebration of his British colleague, responded to the exordium with a contrary (...) claim about the historian’s obligation, namely objectively to render the facts of history without subjective moralizing. Referring to Acton’s lecture, Lea declared. (shrink)

In a series of articles and in a recent book, What Darwin Got Wrong, Jerry Fodor has objected to Darwin’s principle of natural selection on the grounds that it assumes nature has intentions.1 Despite the near universal rejection of Fodor’s argument by biologists and philosophers of biology (myself included),2 I now believe he was almost right. I will show this through a historical examination of a principle that Darwin thought as important as natural selection, his principle of divergence. The principle (...) was designed to explain a phenomenon obvious to any observer of nature, namely, that animals and plants form a hierarchy of clusters. Theodosius Dobzhansky made this the motivating observation of his great synthesizing work, Genetics and the Origin of Species (1937): “the living world is not a single array of individuals in which any two variants are connected by a series of intergrades, but an array of more or less distinctly separate arrays, intermediates between which are absent or at least rare. . . Small.. (shrink)

Ernst Haeckel’s popular book Nat¨urliche Sch¨opfungs- geschichte (Natural history of creation, 1868) represents human species in a hierarchy, from lowest (Papuan and Hottentot) to highest (Caucasian, including the Indo-German and Semitic races). His stem-tree (see Figure 1) of human descent and the racial theories that accompany it have been the focus of several recent books—histories arguing that Haeckel had a unique position in the rise of Nazi biology during the first part of the 20th century. In 1971, Daniel Gasman brought (...) the initial bill of particulars; he portrayed Haeckel as having specific responsibility for Nazi racial programs. He argued that Darwin’s champion had a distinctive authority at the end of the 19th century, throwing into the shadows the myriads of others with similar racial attitudes.1 But it was not simply a general racism that Haeckel expressed; he was, according to Gasman (1971: 157–159), a virulent anti-Semite. Since its original publication, Gasman’s thesis has caught on with a large number of historians, so that in the present period it is usually taken as a truism, an obvious fact of the sordid history of biological thought in the first half of the 20th century.2 Perhaps the most prominent scholar—at least among historians of biology—to adopt and advance Gasman’s contention was Stephen Jay Gould. In his first book, Ontogeny and Phy- logeny (1977), Gould took as his subject Haeckel’s principle of recapitulation, the proposal that during ontogeny the developing embryo went through the same morphological stages as the phylum passed through in its evolutionary descent. So according to this conception, the human embryo begins as a one-celled creature, then takes on the form of an ancient invertebrate (e.g., a gastraea), then of a primitive vertebrate, then of an early mammal, then of a primate, and finally of a distinct.. (shrink)

Chapter III contains several puzzles and unexpected features. The first puzzle regards the chapter’s relationship to Chapter IV: Natural Selection. Both chapters treat of natural selection, so what distinguishes them? Is it that Chapter IV indicates the intelligence behind nature’s selections and Chapter III introduces the analog of intelligence? And is it that Chapter III suggests that natural selection performs an eliminative function, while Chapter IV shows the positive impact of selection? In Chapter IV, and in many subsequent chapters, natural (...) selection, Darwin says, operates only for the good of each individual creature, though Chapter III suggests it destroys most individuals. Darwin asserts that he uses the term “struggle” metaphorically, which raises the question of the explanatory weight his metaphors carry, such metaphors as "the face of nature.” There are a number of unexpected features of Darwin’s analysis displayed in the chapter: for example, his introduction of a new concept of the selective environment and the several experiments he performs to establish his theory, e.g., from mathematical and thought experiments to controlled empirical experiments. Chapter III is a rich though puzzling chapter. (shrink)

In a late reminiscence, Goethe recalled that during his close association with the poet Friedrich Schiller, he was constantly defending “the rights of nature" against his friend's “gospel of freedom.”1 Goethe’s characterization of his own view was artfully ironic, alluding as it did to the French Revolution's proclamation of the "Rights of Man." His remark implied that values lay within nature, values that had authority comparable to those ascribed to human beings by the architects of the Revolution. During the time (...) Goethe made his defense, he also faced another revolution, in which Schiller was a partisan—that of Kant in the intellectual sphere. Both upheavals had undermined the autonomy of nature, replacing her authority with that of human will and understanding. Previous papers in this volume have recorded the shifting fortunes of nature that brought her to this stage of jeopardy. In the early classical period, nature as a unified whole had not yet arisen. Animate and inanimate objects had natures— characteristic modes of action—but there was as yet, according Slatkin, no articulate concept of nature as a whole standing over against human beings. Park has described a long period of transition, when nature became personified in the form of a didactic female, a figure imaginatively based, it would seem, upon the system of a 1 natural philosophy that stood in contrast to the revealed wisdom of God. Nature in this guise yet derived her authority and nurturing capacity from that higher, divine power. During the seventeenth century, writers like Mandeville, as Allen has shown, began to suspect that nature might be a chimera, a fictive creature that disguised humanity's own hidden desires and inclinations. These doubts grew during the next century—with the likes of Hume accelerating the skepticism— till finally, in the two revolutions that so troubled Goethe, nature was completely stripped of her authority. Goethe had become confirmed in his defense of the rights of nature during his travels to Italy during the years 1786-1788. (shrink)

Darwin's theory of natural selection and its moral purpose -- Appendix 1: the logic of Darwin's long argument -- Appendix 2: the historical ontology and location of scientific theories -- Darwin's principle of divergence: why Fodor was almost right -- Darwin's romantic quest: mind, morals, and emotions -- Appendix: assessment of Darwin's moral theory -- The relation of Spencer's evolutionary theory to Darwin's -- Ernst Haeckel's scientific and artistic struggles -- Haeckel's embryos: fraud not proven -- The linguistic creation of (...) man: August Schleicher and the missing link in Darwinian theory -- Was Hitler a Darwinian? (shrink)

Through the last half of the nineteenth century and the first part of the twentieth, no scientist more vigorously defended Darwinian theory than the German Ernst Haeckel (1834–1919). More people learned of the new ideas through his voluminous publications, translated into numerous languages, than through any other source, including Darwin’s own writings. He enraged many of his contemporaries, especially among the religiously orthodox; and the enmity between evolutionary theory and religious fundamentalism that still burns brightly today may in large measure (...) be attributed to Haeckel’s unremitting attacks on the ingressions of religion into science. Though he retained a life-long friendship with and the support of Darwin, some in the scientific community who were critical of evolutionary theory—Emil Du Bois-Reymond, Rudolf Virchow, and Louis Agassiz, for instance—accused him of deception. That charge has been renewed in our time based on seemingly incontrovertible evidence. In a Science magazine article published in 1997, ‘‘Haeckel’s Embryos: Fraud Rediscovered,’’ Haeckel, was indicted of having intentionally misrepresented embryological development (Pennisi 1997). The article reported that the work of Michael Richardson and his colleagues demonstrated this malfeasance through a comparison of Haeckel’s illustrations of early-stage embryos with photographs of the same species at a comparable stage (see Fig. 1). The photos showed embryos of various species that differed among themselves and certainly from Haeckel’s images. The differences were striking and the implication obvious: fraudulent misrepresentation. Richardson, as quoted in the article, affirmed the charge: ‘‘It looks like it’s turning out to be one of the most famous fakes in biology’’. (shrink)

In late September 1838, Darwin read Malthus's Essay on Population, which left him with “a theory by which to work.”115 Yet he waited some twenty years to publish his discovery in the Origin of Species. Those interested in the fine grain of Darwin's development have been curious about this delay. One recent explanation has his hand stayed by fear of reaction to the materialist implications of linking man with animals. “Darwin sensed,” according to Howard Gruber, “that some would object to (...) seeing rudiments of human mentality in animals, while others would recoil at the idea of remnants of animality in man.”116 With this link closed, Darwin hung the materialist chain around his own neck, where it rested most uncomfortably. Stephen Gould, supporting Gruber's argument, finds evidence for this reconstruction in Darwin's M and N notebooks, whichinclude many statements showing that he espoused but feared to expose something he perceived as far more heretical than evolution itself: philosophical materialism-the postulate that matter is the stuff of all existence and that all mental and spiritual phenomena are its by-products. No notion could be more upsetting to the deepest traditions of Western thought than the statement that mind-however complex and powerful-is simply a product of brain.117The proferred hypothesis suggests, then, that Darwin was acutely sensible of the social consequences of equating men with animals and therefore mind with brian, and that he thus shied from publically revealing his views until the intellectual climate became more tolerant.The history I have examined makes this hypothesis implausible. Even if Darwin warily explored the implications of his emerging theory in his notebooks, his subsequent study of Fleming, Wells, Brougham, and Kirby should have quieted any trepidation. If these natural theologians did not flinch at seeing human reason prefigured in the mind of a worm, should Darwin have? Moreover, he recognized in his M notebook that the thesis of evolutionary continuity between men and animals did not require an explicit avowal of his conviction that brain was the agent of thought.118 And in any case, his materialism was of a rather benign sort; at least he so expressed it in an annotation in Abercrombie's Inquiries concerning the Intellectual Powers (1838): “By materialism I mean, merely the intimate connection of thought with form of brain — like kind of attraction with nature of element.”119 This belief would have held little terror for British intellectuals, who were quite familiar — some even comfortable-with Locke's anti-Cartesian argument that there was nothing contradictory in supposing God could make matter to think.120 Finally, even if the intellectual atmosphere of early nineteenth-century Britain were inhospitable to Darwin's brand of materialism, there is little reason to believe he breathed a different air at mid-century while preparing his manuscript.That Darwin should not have feared suspicions of materialism, of course, does not mean that he did not. But I think there were other, more persistent sources of anxiety that kept him from rushing to publish: namely, the several conceptual obstacles he had to overcome if his theory of evolution by natural selection were to be made scientifically acceptable. Prominent among these were the problems surrounding his changing notions of instinct.The inertia of his older ideas about instinct at first made it hard for Darwin to gauge how far the theory of natural selection might be applied to behavior. By the early 1840s he finally felt ready to meet the challenge of the natural theologians by providing a naturalistic explanation for the wonderful instincts of animals. In his “Essays” of 1842 and 1844 one sort of instinct is, however, not considered-that of neuter insects. Yet Darwin seems to have appreciated the difficulties such instincts entailed at least by 1843, when he read Kirby and Spence. He simply required time to work out a solution to a problem he initially perceived as “fatal to my whole theory.” Even while writing the “Species Book” in the summer of 1857, he was still juggling several possible solutions compatible with natural selection. It was only a short time before he actually turned to work on the Origin of Species that he appears to have settled on a single explanation for the difficulties posed by the instincts of worker bees and ants. The force of his theory of community selection snapped the last critical support of the creationist hypothesis and, conveniently enough, also fractured the generalized Lamarckian account of the evolution of behavior. These results were worth waiting for. (shrink)

Several scholars and many religiously conservative thinkers have recently charged that Hitler’s ideas about race and racial struggle derived from the theories of Charles Darwin (1809-1882), either directly or through intermediate sources. So, for example, the historian Richard Weikart, in his book From Darwin to Hitler , maintains: “No matter how crooked the road was from Darwin to Hitler, clearly Darwinism and eugenics smoothed the path for Nazi ideology, especially for the Nazi stress on expansion, war, racial struggle, and (...) racial extermination.” In a subsequent book, Hitler’s Ethic: The Nazi Pursuit of Evolutionary Progress, Weikart argues that Darwin’s “evolutionary ethics drove him [Hitler] to engage in behavior that the rest of us consider abominable.” Other critics have also attempted to forge a strong link between Darwin’s theory and Hitler’s biological notions. In the 2008 film “Expelled,” a documentary defense of Intelligent Design, the Princeton trained philosopher David Berlinski, in conversation with Weikart, confidently asserts: “If you open Mein Kampf and read it, especially if you can read it in German, the correspondence between Darwinian ideas and Nazi ideas just leaps from the page.” John Gray, former professor at the London School of Economics, does allow that Hitler’s Darwinism was “vulgar.” Hannah Arendt also appears to have endorsed the connection when she declared: “Underlying the Nazis’ belief in race laws as the expression of the law of nature in man, is Darwin’s idea of man as the product of a natural development which does not necessarily stop with the present species of human being.” Put “Darwin” and “Hitler” in a search engine and several million hits will be returned, most from religiously and politically conservative websites, articles, and books. (shrink)